84-1601-65 [取扱停止]MARCH4, CT (MARCH4, KIAA1399, RNF174, E3 ubiquitin-protein ligase MARCH4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174) (APC) 200ul 038195-APC
84-1601-65 [取扱停止]MARCH4, CT (MARCH4, KIAA1399, RNF174, E3 ubiquitin-protein ligase MARCH4, Membrane-associated RING finger protein 4, Membrane-associated RING-CH protein IV, RING finger protein 174) (APC) 200ul 038195-APC
MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19).
MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments.
MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).
Applications:Suitable for use in Western Blot, FLISA
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:FLISA WB
Calc Crossreactivity:Hu
Immunogen:MARCH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of human MARCH4.