Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins.
Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin.
ILK encodes a predicted 451-amino acid protein, with an apparent molecular weight of 59 kD.
The ILK protein is a serine/threonine protein kinase with 4 ankyrin-like repeats.
ILK regulates integrin-mediated signal transduction.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:ILK1/ILK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19~49 amino acids from the N-terminal region of human ILK1/ILK2.