The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events.
Cleavage of the precursor generates alpha and beta subunits.
It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
The protein possess tyrosine kinase activity.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Recommended Dilution:Optimal dilution determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-89 amino acids from the N-terminal region of human IGF1R.
