Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions.
LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.
LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development.
LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
[provided by RefSeq].
Applications:Suitable for use in Dot Blot, ELISA
Recommended Dilution:ELISA: 1:1,000Dot blot 1:100-500
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：DB E
Calc Crossreactivity：Hu
Immunogen：Phospho-LIMK1 (Thr508) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Thr508 of human LIMK1.
