84-1537-28　［取扱停止］RNF128, ID (RNF128, GRAIL, E3 ubiquitin-protein ligase RNF128, Gene related to anergy in lymphocytes protein, RING finger protein 128) (AP) 200ul　041110-AP

特徴

• The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway.
• This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity.
• Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production.
• Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.
• Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.