This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain.
This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking.
The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity.
Mutations in this gene have been associated with early-onset familial Alzheimer's disease.
This gene has a pseudogene on chromosome 8.
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：TMED10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-185 amino acids from the C-terminal region of human TMED10.
