This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway.
The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4.
Mutations in this gene have been linked to progressive myoclonus epilepsy.
Alternate splicing results in multiple transcript variants.
A pseudogene of this gene is found on chromosome 3.
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 677-704 amino acids selected from the C-terminal region of human PRICKLE1.
