The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains.
It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes.
The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex.
This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex.
The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：GTF3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-334 amino acids from the C-terminal region of human GTF3A.
