NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation.
May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors.
Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver.
May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：NR5A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human NR5A2.
