The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif.
PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes.
This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane.
The surface membrane association of this protein depends on its C-terminal prenylation.
Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis.
Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human, mouse
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-168 amino acids from the C-terminal region of human PTP4A1.
