Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways.
SH3 domain binding glutamic acid-rich protein (SH3BGR), also designated 21-glutamic acid-rich protein (21-GARP), is a 239-amino acid protein differentially expressed in heart and skeletal muscle.
Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure.
SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：SH3BGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-177 amino acids from the Central region of human SH3BGR.
