This gene encodes the D2 subtype of the dopamine receptor.
This G-protein coupled receptor inhibits adenylyl cyclase activity.
A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia.
Alternative splicing of this gene results in two transcript variants encoding different isoforms.
A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
Applications:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes human DRD2.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 307-336 in the C-terminal region of human DRD2. Species Sequence Homology: mouse