84-1513-37 ［取扱停止］PLEKHF1, NT (PLEKHF1, APPD, LAPF, ZFYVE15, Pleckstrin homology domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15) (AP) 200ul 040158-AP
84-1513-37 ［取扱停止］PLEKHF1, NT (PLEKHF1, APPD, LAPF, ZFYVE15, Pleckstrin homology domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15) (AP) 200ul 040158-AP
PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway.
Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm.
Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Recognizes human PLEKHF1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 51-79 in the N-terminal region of human PLEKHF1.
