Serine/threonine protein kinase which forms a receptor complex on ligand binding.
The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases.
Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3.
Receptor for activin AB, activin B and NODAL.
Plays a role in cell differentiation, growth arrest and apoptosis.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes mouse Acvr1c
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 341-368 in the C-terminal region of mouse Acvr1c. Species sequence homology: human, rat