CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle.
The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly.
In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.
Applications:Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution:ELISA: 1:1,000 Western Blot: 1:100-500Immunohistochemistry: 1:10-501:10-50
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：CDCA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122~152 amino acids from the center region of human CDCA8.
