The protein encoded by this gene acts as receptor for arginine vasopressin.
This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors.
Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system.
The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release.
It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome.
A spliced antisense transcript of this gene has been reported but its function is not known.
Applications:Suitable for use in Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Recognizes human AVPR1B.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 289-317 in the C-terminal region of human AVPR1B, Swiss/UniProt Accession: P47901
