CDH4 is a classical cadherin from the cadherin superfamily.
It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.
Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth.
In addition, a role in kidney and muscle development is indicated.
Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines.
Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by peptide immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu
Immunogen：CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182~211 amino acids from the N-terminal region of human CDH4.
