This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis.
The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain.
The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions.
The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.
Alternatively spliced transcript variants encoding the same protein have been identified.
[provided by RefSeq].
Applications:Suitable for use in Western Blot, ELISA
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：TRIM37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 935-964 amino acids from the C-terminal region of human TRIM37.
