Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules.
Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain.
The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains.
This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes human Myeloperoxidase.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to a portion within aa 60-89 from the N-terminal region of human Myeloperoxidase (NP_000241), conjugated to KLH.