This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver.
The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes.
The gene is within the Smith-Magenis syndrome region on chromosome 17.
Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
Applications:Suitable for use in Western Blot, ELISA and Immunohistochemistry
Recommended Dilution:ELISA: 1:1,000 Western Blot: 1:50-100Immunohistochemistry: 1:10-50
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A/G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes human PEMT. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human PEMT, UniProt Accession #Q9UBM1.