RSK3 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases.
This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.
The activity of this protein has been implicated in controlling cell growth and differentiation.
Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
Applications:Suitable for use in ELISA and Dot Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000 Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes human RPS6KA3 when phosphorylated at Ser369.
Isotype:IgG
Calc Applications Abbrev:DB E
Calc Crossreactivity:Hu
Immunogen:Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser369 of human RPS6KA3 (KLH).