PIM1, which belongs to the Serine/Threonine protein kinase family, is thought to play a role in signal transduction in blood cells.
The protooncogene PIM1 encodes a protein kinase upregulated in prostate cancer.
It may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3.
PIM1 is expressed primarily in cells of the hematopoietic and germ line lineages.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: Formalin-fixed, paraffin-embedded sectionsOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A/G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Recognizes human Pim1.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 374-404 in the C-terminal region of human Pim1, UniProt Accession #P11309. Species sequence homology: bovine
