NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family.
It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR).
This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex.
This complex plays a central role in inducing gene transcription during the immune response.
Applications:Suitable for use in ELISA and Dot Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000 Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity:Recognizes human NFATC2 when phosphorylated at Ser330.
Isotype:IgG
Calc Applications Abbrev:DB E
Calc Crossreactivity:Hu
Immunogen:Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser330 of human NFATC2 (KLH).