PIASz is a members of the PIAS (protein inhibitor of activated signal transducer and activator of transcription) family of proteins, negative regulators of the Janus family of tyrosine kinase (JAK)-signal transducer and activator of transcription pathway.
PIAS proteins have been shown to act as transcriptional co-regulators of multiple signaling pathways in various cellular processes.
PIASz increases ligand-dependent transcriptional activity of androgen receptor and other nuclear hormone receptors, possibly through alteration of chromatin structure by SWI/SNF-like BAF complexes
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1,000Immunohistochemistry: 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Specificity：Recognizes human ZMIZ2.
Isotype：IgG
Calc Applications Abbrev：E IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide selected from the C-terminal region of human PIASz1 (KLH).
