84-1417-85　Angiopoietin 1 (ANG-1, ANGPT1, KIAA0003, Angiopoietin-1) 200ul　139217

特徴

• Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1.Angiopoietin-1 (Ang1) and Angiopoietin-2 (Ang2) are ligands that regulate tyrosine phosphorylation of the Tie2/Tek receptor on endothelial cells.
• Proper regulation of Tie2/Tek is required for normal vascular development, by regulating vascular remodeling and endothelial cell interactions.
• Antiopoietin-2 (Ang2) is an antagonist of Ang1 that competes for binding of the Tie2 receptor and blocks Ang-1 induced Tie2 phosphorylation during vasculogenesis.
• Angiopoietins are proteins with important roles in vascular development and angiogenesis.
• All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry and ELISA.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:100-200Western Blot: 1:100-400Immunocytochemistry: 1:100-500 Immunohistochemistry (frozen): 1:100-500 Immunohistochemistry (paraffin sections): 1:50-200 Optimal dilutions to be determined by the researcher.
• Positive Control (supplied):139217A Suppled as a recombinant in loading buffer
• DAB: 10ul/wellECL: 5ul/well
• AA Sequence:MGHHHHHHSG S- NQRRSPENSG RRYNRIQHGQ CAYTFILPEH DGNCRESTTD QYNTNALQRD APHVEPDFSS QKLQHLEHVM ENYTQWLQKL ENYIVENMKS EMAQIQQNAV QNHTATMLEI GTSLLSQTAE QTRKLTDVET QVLNQTSRLE IQLLENSLST YKLEKQLLQQ TNEILKIHEK NSLLEHKILE MEGKHKEELD TLKEEKENLQ GLVTRQTY
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.