LOR is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells.
Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.LOR encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells.
Mutations in LOR may be the cause of both Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases.
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 5ug/mlImmunohistochemistry: 4-8ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human Loricrin. Species Crossreactivity: bovine, guinea pig and mouse
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Bo Gp Hu Mo
Immunogen：Synthetic peptide corresponding to GYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG at the N-terminus of human LOR.
