Oxytocin is a mammalian hormone that acts primarily as a neuromodulator in the brain.
The receptor is a G-protein-coupled receptor which requires Mg2+ and cholesterol.
It belongs to the rhodopsin-type (class I) group of G-protein-coupled receptors.
Oxytocin receptors are expressed by neurons in many parts of the brain and spinal cord, including the amygdala, ventromedial hypothalamus, septum, nucleus accumbens and brainstem.
It is invlolved in regulating mood including perceptions of stress and stress induced depression.
Oxytocin may play a role in autism and may be an effective treatment for related repetitive and affiliative behaviors.
It is also know to produce antinociception and analgesia making it a target for certain pain therapies.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:5000-1:10,000 (in PBS/0.3% Triton X-100 using Cy3 technique)1:10,000-1:15,000 (in PBS/0.3% Triton X-100 using Bn/Av-HRP technique)Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：rat
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder, 0.09% sodium azide. Reconstitute with 100ul of distilled or deionized dH2O.
Specificity：Recognizes rat Oxytocin.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Rt
Immunogen：Synthetic oxytocin coupled to BTg with carbodiimide (CDI) linker.
