Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate.
Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8.
mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells.
mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
Applications:Suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: 1:200-1:600Immunofluorescence: 1:200Western Blot: 1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：guinea pig
Source Antibody：rat
Grade：Serum
Purity：Serum
Form：Supplied as a liquid in PBS, 0.05% sodium azide.
Specificity：Recognizes rat mGluR6. Species Crossreactivity: mouse.
Isotype：IgG
Calc Applications Abbrev：IF IHC WB
Calc Crossreactivity：Mo Rt
Immunogen：AAPPQNENAEDAK, corresponding to the C-terminus of rat mGluR6.
