LOXL2 is a member of the lysyl oxidase gene family.
This family of extracellular, copper dependent enzymes participates in the post-translational modification essential to the biogenesis of connective tissue by deaminating the side chains of lysine residues in collagen and elastin.
This results in the covalent cross-linking of fibrillar collagen and the formation of desmosine and isodesmosine cross-links in elastin.
Members of the lysyl oxidase family play a role in tumor suppression, cell adhesion and senescence.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Paraffin): 15ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human LOXL2. Species sequence homology: Gorilla, orangutan, monkey, marmoset, canine, bovine, Bbt, elephant, panda, equine, rabbit (100%), mouse, rat, opossum, turkey, chicken, platypus (93%), xenopus, pufferfish, zebrafish, stickleback (87%).
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 15aa from human LOXL2 at N-Terminal.
