BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection.
Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes (Yokomizo et al., 1997).
Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor ( Yokomizo et al., 1997).
Part of the coding regions of BLTR2 have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 and CIDE-B on chromosome 14.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:200Immunohistochemistry (Parafin): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in TBS pH 7.4, 0.5mg/ml BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human BLT1. Species Crossreactivity: Bovine. Does not react with mouse.
Isotype：IgG
Calc Applications Abbrev：IC IHC WB
Calc Crossreactivity：Bo Hu
Immunogen：Synthetic peptide corresponding to aa331-352 from human BLT1 (ALEPGPSESLTASSPLKLNELN).
