Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins.
The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 ('VLA-3'), very common antigen 2 ('VCA-2'), extracellular matrix receptor 1 ('ECMR1'), and galactoprotein b3 ('GAPB3').
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Paraffn): 7.5-10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human ITGA3/CD49c. Species sequence homology: Gorilla (100%), monkey (100%), bovine (100%), marmoset (94%), mouse (94%), canine (94%), bat (94%), hamster (94%), elephant (94%), equine (94%), opossum (94%), rabbit (89%).
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 18aa from human ITGA3/CD49c atN-Terminal.