Cacna2d1 is an alpha subunit 2/delta regulatory subunit of the voltage-gated calcium channel that is important for functional channel assembly.
In vitro studies have shown that this subunit is the binding site for gabapentin, an anticonvulsant that exerts antihyperalgesic effects by unknown mechanisms.
Increased expression of this subunit in the spinal cord and dorsal root ganglia (DRG) is associated with enhanced nociceptive responses of spinal nerve-injured rats to innocuous mechanical stimulation (allodynia).
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500 -1:5000Immunohistochemistry (Paraffin): 10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Supernatant
Purity：Supernatant.
Form：Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Specificity：Recognizes human CACNA2D1.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to human CACNA2D1.
