Angiopoietins are proteins with important roles in vascular development and angiogenesis.
All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor.
The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation.
It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme.
The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot 1-2ug/mlImmunohistochemistry (Paraffin): 2.5ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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仕様
Size：50ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity：Recognizes human ANGPT1. Species sequence homology: Rat (90%), sheep (90%), bovine (90%), porcine (90%), xenopus (90%), Aaabidopsis (80%), paramecium (80%)
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Bo Ca Eq Hu Mc Mk Mo Po Rb Rt Sh Xe
Immunogen：Synthetic peptide corresponding to C-PDFSSQKLQH from human ANGPT1/Angiopoietin-1.
