84-1382-85　PLEKHA1 (Pleckstrin Homology Domain-containing Family A Member 1, PH Domain-containing Family A Member 1, TAPP1, Tandem PH Domain-containing Protein 1, TAPP-1) 100ul　131450

特徴

• This gene encodes a pleckstrin homology domain-containing adapter protein.
• The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate.
• This protein may be involved in the formation of signaling complexes in the plasma membrane.
• Polymorphisms in this gene are associated with age-related macular degeneration.
• Alternate splicing results in multiple transcript variants.
• A pseudogene of this gene is found on chromosome 5.
• Applications:Suitable for use in Western Blot and Immunoprecipitation.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• AA Sequence:MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTREDSFVWYMDNPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLNKAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPIITPTQKEEVNECGESIDRNNLKRSQSHLPYFTPKPPQDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRVIPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQADSPEEMHSWIKAVSGAIVAQRGPGRSASSEHPPGPSESKHAFRPTNAATATSHSTASRSNSLVSTFTMEKRGFYESLAKVKPGNFKVQTVSPREPASKVTEQALLRPQSKNGPQEKDCDLVDLDDASLPVSDV
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.