This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase.
The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate.
This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration.
Mutations at this locus have been associated with lethal congenital contractural syndrome.
Alternatively spliced transcript variants encoding different isoforms have been described.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MTPRHPLFTSRRPPAQPTRCARKAPAVEKPDPSPRSPARTHTPREQPLHSAQERGRPSSGTGQPRGSQHPSGQAHVGSSLRAQRVCPALGSDLGLSSQPGAHLLAPGIHPSAPALSLRRTPSRHPPGRQGQRSEGVSGTWMASRDRGIVISKAQPPEATPVLPGSPRVALPRALAPETPRACGVTRSSRCGPGRAAPRPGQPPSAE
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2.
Specificity：Recognizes human PIP5K1C.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Full length human PIP5K1C, aa1-206 (AAH11138.1).
