KiSS-1 has been reported to suppress metastases of melanomas and breast carcinomas without affecting tumorigenicity.
Human KiSS-1 transcripts are predominately expressed in the brain and placenta.
Expression of KiSS-1 reduces the level of NFkB p50/p65 binding to the MMP9 promoter and correlates with diminished expression of the 92kD type IV collagenase (MMP-9).
KiSS-1 may regulate events downstream of cell-matrix adhesion in mechanisms involving cytoskeletal reorganization.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
AA Sequence:MNSLVSWQLLLFLCATHFGEPLEKVASVGNSRPTGQQLESLGLLAPGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRG
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2.
Specificity：Recognizes human KISS1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Full length human KISS1, aa1-138 (NP_002247.3).
