84-1347-67　CYP3A43 (Cytochrome P450, family 3, subfamily A, polypeptide 43) 100ul　125586

特徴

• Cytochromes P450 are a group of heme-thiolate monooxygenases.
• In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.
• It performs a variety of oxidation reactions (e.g.
• caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
• The enzyme also hydroxylates etoposide.
• Applications:Suitable for use in Immunoprecipitation.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Amino Acid Sequence:MNLETGNGPHHFPMWRYVGEKPEAGSREQQVHQLERFLWGLHHGCNHWHIIWSELGFSQQSTRSLSEKYEEAFKIGFFGSLFTLNIQSLAVLPRPECMVRSGLTETSTSWVRVILLPQPPEELGLQHRVDFFQQIIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERSH
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.