This proapoptotic activity is mediated predominantly through the activation of caspase-9.
It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.
Applications:Suitable for use in Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot.
Other applications not tested.
Recommended Dilution:Immunocytochemistry: 1:200Immunohistochemistry: 1:500; paraffin sectionsImmunoprecipitation: 1:200Western Blot: 1:1000Optimal dilutions to be determined by researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 10% glycerol, 0.02% sodium azide.
Specificity：Recognizes human and mouse Asc.
Isotype：IgG
Calc Applications Abbrev：IC IHC IP WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to aa at the N-terminal human Asc.
