It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia.
The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins.
This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Immunohistochemistry: 1:10-1:50Flow Cytometry: 1:10-1:50Immunofluorescence: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human BCL3. Species crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:FC IF IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to a portion of amino acids within aa249-277 from the center region of human BCL3, conjugated to KLH (P20749).