It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches.
MYH is involved in oxidative DNA damage repair.
It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone.
It possesses both adenine and 2-OH-A DNA glycosylase activities.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Indirect Flow Cytometry.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Indirect Flow Cytometry: 1:10-1:50Immunofluorescence: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human MUTYH. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E FC IF WB
Calc Crossreactivity：Hu Mo
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 341-367 in the central region of human MUTYH.
