This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family.
HMG proteins function as architectural factors and are essential components of the enhancesome.
This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor.
Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation.
A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human HMGA2.
Isotype：IgG
Calc Applications Abbrev：E FC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 64-92 in the C-terminal region of human HMGA2, UniProt Accession #P52926. Species sequence homology: mouse
