OPN1MW encodes for a light absorbing visual pigment of the opsin gene family.
The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin.
Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain.
The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences.
X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes.
Defects in this gene are the cause of deutanopic colorblindness.
Applications:Suitable for use in Western Blot, Flow Cytometry and ELISA.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:1000Flow Cytometry (Indirect): 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Specificity:Recognizes human OPN1MW
Isotype:IgG
Calc Applications Abbrev:E FC WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 21-50 in the N-terminal region of human OPN1MW. Species Sequence Homology: chicken, rat, Xenopus