84-1315-43　CBL, CT (RING finger protein 55, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, Signal transduction protein CBL, E3 ubiquitin-protein ligase CBL,RNF55, CBL2, CBL) 200ul　033239

特徴

• The CBL oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas.
• As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains.
• Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
• Applications:Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
• Recommended Dilution:ELISA: 1:1,000Western Blot: 1:50-100Indirect Flow Cytometry: 1:10-50
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.