Required for autophagosome formation (By similarity).
Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity).
Phosphorylates ATG13/KIAA0652.
Involved in axon growth (By similarity).
Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
Applications:Suitable for use in Dot Blot.
Other applications not tested.
Recommended Dilution:Dot Blot: 1:500Optimal dilution to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human ULK1 when phosphorylated at Ser317.
Isotype:IgG
Calc Applications Abbrev:DB E
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S317 of human ULK1.