84-1314-24 SQSTM1, phosphorylated (S403) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62) 200ul 042284
84-1314-24 SQSTM1, phosphorylated (S403) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62) 200ul 042284
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.
The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.
Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.
Mutations in this gene result in sporadic and familial Paget disease of bone.
Applications:Suitable for use in Dot Blot, ELISA
Recommended Dilution:ELISA: 1:1,000Dot blot 1:500
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：DB E
Calc Crossreactivity：Hu
Immunogen：SQSTM1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S403 of human SQSTM1.
