84-1314-23 SQSTM1, phosphorylated (S207) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62) 200ul 042283
84-1314-23 SQSTM1, phosphorylated (S207) (SQSTM1, ORCA, OSIL, Sequestosome-1, EBI3-associated protein of 60kD, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62kD, Ubiquitin-binding protein p62) 200ul 042283
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.
The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.
Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene.
Mutations in this gene result in sporadic and familial Paget disease of bone.
Applications:Suitable for use in Dot Blot and ELISA.
Other applications not tested.
Recommended Dilutions:Dot Blot: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human SQSTM1.
Isotype：IgG
Calc Applications Abbrev：DB E
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues surrounding S207 of human SQSTM1, UniProt Accession #NP_001135770.1; Q13501.
