Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
This protein is the integrin alpha 5 chain.
Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor.
In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Applications:Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA.
Other applications have not been tested.
Recommended Dilution:Western Blot: 1:1000Indirect Flow Cytometry: 1:10-1:50Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified by ammonium sulfate precipitation.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes human CD49e. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E FC WB
Calc Crossreactivity:Hu Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 796-824 in the C-terminal region of human CD49e.