Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development.
NeuroG1 is a bHLH protein with dual cell-fate specification roles.
It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes.
NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.
Applications:Suitable for use in Western Blot, ELISA
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：NeuroG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38~68 amino acids from the N-terminal region of human NeuroG1.
