84-1305-89　RNF128, ID (RNF128, GRAIL, E3 ubiquitin-protein ligase RNF128, Gene related to anergy in lymphocytes protein, RING finger protein 128) 200ul　041110

特徴

• The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway.
• This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity.
• Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production.
• Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.
• Alternatively spliced transcript variants encoding distinct isoforms have been reported.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.