Trem2 may have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines.
Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Applications:Suitable for use in Immunohistochemistry, Western Blot and ELISA.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 1:500-1:1000Immunohistochemistry (Leica/Paraffin): 1:500 Requires HIER using EDTA pH 9.0Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:Recognizes mouse Trem2.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Mo
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 22-48 in the N-terminal region of mouse Trem2.